書誌： European Journal of Neuroscience , 2010
European Journal of Neuroscience Volume 13, Issue 6, pages 1190–1196, March 2010
Hisanori Wakamatsu,Yuko Yoshinobu, Reiko Aida, Takahiro Moriya, Masashi Akiyama1 and Shigenobu Shibata
Abstract Daily restricted feeding entrains the circadian rhythm of mouse clock gene expression in the central nervous system excluding the suprachiasmatic nucleus, as well as in the peripheral tissues such as the liver, lungs, and heart. In addition to entrainment of the clock gene, daily restricted feeding induces a locomotor activity increase 2–3 h before the restricted feeding time. The increase of activity is called the food anticipatory activity (FAA). At present, the mechanisms for restricted feeding-induced entrainment are still unknown. In this review, we describe the role of the central nervous system and peripheral tissues in FAA performance and also in entrainment of clock gene expression.
Key words: chrononutrition, clock gene, food anticipation, hypothalamus, liver.